Discover more about the latest QCI update and how the platform simplifies and accelerates NGS variant analysis, interpretation, and reporting
We are pleased to announce a minor update to QIAGEN Clinical Insight (QCI), a clinical informatics platform for streamlined NGS variant analysis, interpretation, and reporting of oncology and inherited disease tests. The update adds new features, functionalities, and improvements, further enhancing QCI's ease-of-use, performance, and responsiveness.
New QCI features and functionalities
- Performance improvements – Updates to the user-interface that limit the amount of processing needed to render the application. This has resulted in significant improvements in performance and responsiveness. In addition, users will now be informed about expected processing times.
- New Genetic Analysis filter – A Genetic Analysis filter that enables users to filter (exclude/include) variants of specific genotypes.
- Display CADD and HGMD annotations in Variants View – For hereditary workflow users can now bring CADD and HGMD annotations to the Variants View for quick lookups and sorting of CADD scores. Plus for HGMD users, now included are annotations link outs to the variant’s HGMD mutation detail page.
- Improved sample uploader – Users can load new samples without waiting for an existing sample to complete processing.
- Support for .PED file – Family/trio analysis can have sample relationships described via .PED file format. This metadata describes family relationships similar to how the existing JSON format supports relationships in prior versions.
- New Application Programming Interface (API) endpoint – New API for developers to integrate existing LIMS/informatics system with QCI Interpret Translational to automate the upload of samples.
Explore the QCI portfolio
- QCI Interpret Translational - A NGS variant assessment software solution that enables rapid, evidence-powered variant annotation, filtering, and triage for human exome, genome, and large cohort sequencing data.
- QCI Interpret - Clinical decision support software for molecular diagnostic labs that enables faster turnaround times, higher confidence reporting, and test menu expansion for oncology and inherited diseases.
- QCI Interpret One - Clinical decision support software integrated with professional variant interpretation services that enables molecular diagnostic labs to perform rapid, evidence-based reporting of oncology NGS tests at scale.
- QCI Precision Insights - A professional clinical interpretation service for oncology NGS tests that translates molecular data specific to each patient into clinical insights and therapeutic options.
We are excited to announce the general availability of the Fall 2020 Release of QIAGEN Clinical Insight (QCI) Interpret. This new release brings the following new features:
- We’ve added new variant triaging capabilities into QCI Interpret to allow filtering based on sequencing and upstream artifacts (Confidence Filter), population frequency (Common Variants Filter), pathogenicity (Predicted Deleterious Filter), and biological relevance (Biological Context).
- A new workflow has been introduced to allow test creation from sample inventory, as well as supporting legacy sample upload and analysis.
- Inventoried somatic samples can be used for multi-sample somatic analysis (ex. time-based samples).
- We’ve made changes to the variant list page to better cluster relevant genes/variants, as well as updated/added new view settings.
- This release also features the ability to export the annotations associated with filtered variants in the variants table.
- A new addition is the MITOMAP content for better annotating mitochondrial variants.
- QCI Interpret One is now available in Europe containing EU-specific content.
To learn more about the new features and functionalities of QCI Interpret, please attend our free webinar on November 10 at 11 AM EST. Register here.
If you are a current QCI customer and have questions about the new release, please contact support at ts-bioinformatics@qiagen.com.