In this 90-minute training on QIAGEN OmicSoft and Ingenuity Pathway Analysis (IPA), we’ll cover how to easily query inflammatory conditions related to public data (GEO, SRA and more) to:
• Rapidly query and identify public datasets that fit our search criteria
• Discover and validate biomarker expression in disease tissue, different treatments and response groups
• Identify a list of biomarkers specific to a condition (non-responders, disease-specific, cell-type specific and more)
• Confirm condition-specific biomarkers through gene expression heatmaps
• Investigate biological mechanisms through network study
Additional QIAGEN Digital Insights scientists will be on the call to answer your questions and help with other inquiries, such as how to install the software, etc.
In this training, attendees will learn how to harness curated ‘omics datasets in OmicSoft DiseaseLand and curated research findings in IPA to discover new potential biomarkers. Using a neurological disorder as a case study, we will:
• Search public RNA-Seq datasets for tissue- and disease-specific differential expression in brain
• Identify genes whose expression correlates with our factor within a sample group
• Prioritize candidate biomarkers by disease vs. normal expression
• Simulate biomarker activity changes to determine potential mechanisms of action
Investigation of inflammatory, infectious, oncological, and other disorders can also be done using similar approach and will be highlighted during this training.
Click here to register.
OncoLand is a sophisticated oncology-focused database designed to accelerate cancer research. Integrating published research and large consortium cancer datasets, robust data visualization and discovery tools, OncoLand saves you valuable time and resources in your pursuit for actionable discoveries.
Start your free trial of OncoLand today!
OmicSoft DiseaseLand is the disease-focused platform designed to help you harness thousands of disease-focused datasets to accelerate biological discovery. Bringing together robust data visualization and analytics tools, OmicSoft “Land” technology rapidly connects you to the most relevant insights. Explore gene expression data at the gene, transcript, and exon level, as well as whole-transcriptome analyses of differential expression. Every project in DiseaseLand is carefully curated and processed through common pipelines, allowing you to quickly find the most relevant results across projects. DiseaseLand saves you valuable time and resources, enabling you to focus on your research.
Start your free trial of DiseaseLand today!
Learn about added content and features of PGMD, the PharmacoGenomic Mutation Database, which are making it even easier to look up the set of variants that are relevant to a particular drug, disease or gene:
Biomedical Genomics Workbench provides a complete solution for NGS data analysis for biomarker discovery. It is fast, intuitive, and easy to use, and at the same time, it's flexible and customizable. It enables you to get accurate and trustworthy results from whole genome, exome, targeted amplicon, transcriptome as well as epigenetic NGS data in one step. You can spend only half the time compared to open source solutions, while realizing greater than 95% sensitivity for the detection of germline and low frequency variants, including CNV with high specificity.
In addition Biomedical Genomics Workbench provides specific functionalities for cancer, hereditary, and rare diseases data analysis and advanced visualization for validation of results:
And of course, Biomedical Genomics Workbench is part of QIAGEN’s sample-to-insight workflow:
